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211 results

Bioequivalence study of Fixed Dose Combination Gliclazide 60 mg + Metformin 1000 mg extended release tablet under fasting conditions

Servier Protocol Code
S005189-201
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Trial Details
Not yet recruiting

Bioequivalence of One Tablet of Gliclazide MR 90 mg (S005190) and One and a Half Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fed Conditions.

Servier Protocol Code
S005190-205
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Trial Details
Completed

Bioequivalence of One Tablet of Gliclazide MR 120 mg (S005190) and Two Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fed Conditions.

Servier Protocol Code
S005190-204
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Trial Details
Completed

Bioequivalence of One Tablet of Gliclazide MR 120 mg (S005190) and Two Tablets of Gliclazide MR 60 mg (Diamicron® MR) in Healthy Participants under Fasting Conditions

Servier Protocol Code
S005190-203
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Trial Details
Completed

Multiple-Dose Study on the Bioequivalence of One Tablet of Gliclazide MR 120 mg (S005190) and Two Tablets of Gliclazide MR 60 mg (Diaprel® MR) in Healthy Participants under Fed Conditions.

Servier Protocol Code
S005190-206
EU Trial (CTIS) Number
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Trial Details
Terminated

A Phase Ib/II first-in-human, multicentre, open-label, multiple ascending dose study of S230815 in paediatric participants with KCNT1-related Developmental and Epileptic Encephalopathy

Servier Protocol Code
CL1-230815-001
Clinicaltrials.gov Identifier
EU Trial (CTIS) Number
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Trial Details
Recruiting

A study to evaluate the efficacy and safety of gliclazide MR in patients with type 2 diabetes inadequately controlled with dapagliflozin with or without metformin

Servier Protocol Code
S005201-175
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Trial Details
Completed

Exploratory Bioavailability of Three Formulations of Gliclazide MR Tablets 120 mg (I.R.I.S.) in Healthy Volunteers Under Fed Conditions (High Fat High Calorie Meal and Standard Meal)

Servier Protocol Code
S005190-213
EU Trial (CTIS) Number
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

Comparative pharmacokinetic study of three prolonged release formulations and one immediate release formulation of S221237 after single oral administration in fed conditions. An open-label, randomized, four-period, four-sequence, one-way cross-over, single center, phase I study in Caucasian healthy male participants.

Servier Protocol Code
S221237-176
EU Trial (CTIS) Number
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen (CHONQUER)

Servier Protocol Code
CL3-95031-007
Clinicaltrials.gov Identifier
EU Trial (CTIS) Number
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

Exploratory bioavailability of two formulations of gliclazide MR tablets 120 mg (I.R.I.S.) in healthy volunteers under fed and fasting conditions

Servier Protocol Code
S005190-170
EU Trial (CTIS) Number
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

A Phase 1, Open-Label, Multicenter Trial Investigating the Safety, Tolerability, and Preliminary Antineoplastic Activity of Sym021 (Anti-PD-1) as Monotherapy, in Combination With Either Sym022 (Anti-LAG-3) or Sym023 (Anti-TIM-3), and in Combination With Both Sym022 and Sym023 in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Servier Protocol Code
SYM021-01
Clinicaltrials.gov Identifier
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

Study assessing the glucose-lowering efficacy and safety of luseogliflozin on top of metformin in Caucasian patients with type 2 diabetes mellitus

Servier Protocol Code
CL3-LUSEO-001
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

Evaluation of the clinical efficacy and safety of perindopril 10 mg/indapamide 2.5 mg/amlodipine 5 or 10 mg/bisoprolol 5 mg in single-pill combination after 8 weeks of treatment versus the free combination of perindopril 10 mg, indapamide 2.5 mg and amlodipine 5 or 10 mg in patients with uncontrolled essential hypertension. An international, multicentre, randomised, double-blind, 16-week study.

Servier Protocol Code
CL3-05179-002
EudraCT Number
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

A Multicentre, Randomized, Double-blind, Placebo-controlled Dose-finding Study of S62798 in Patients with Intermediate-High Risk Acute Pulmonary Embolism on heparin

Servier Protocol Code
CL2-62798-010
EudraCT Number
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

Phase I / II, Open Label, Dose Escalation Part (Phase I) Followed by Noncomparative Expansion Part (Phase II), Multi-centre Study, Evaluating Safety, Pharmacokinetics and Efficacy of S65487, a Bcl2 Inhibitor Combined With Azacitidine in Adult Patients With Previously Untreated Acute Myeloid Leukemia Not Eligible for Intensive Treatment

Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

An open-label, randomised, phase III study comparing trifluridine/tipiracil in combination with bevacizumab to trifluridine/tipiracil monotherapy in patients with refractory metastatic colorectal cancer

Servier Protocol Code
CL3-95005-007
Clinicaltrials.gov Identifier
EudraCT Number
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

A Phase I/II, open label, non-randomized study to evaluate safety, tolerability, pharmacokinetics and clinical activity of S64315 in patients with locally advanced or metastatic breast cancer in combination with various standard treatments including hormonal and cytotoxic agents

Servier Protocol Code
CL1-64315-003
EudraCT Number
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

Efficacy and safety of 3 doses of S201086/GLPG1972 administered orally once daily in patients with knee osteoarthritis. A 52-week international, multi-regional, multi-center, randomized, double-blind, placebo-controlled, dose-ranging study.

Servier Protocol Code
CL2-201086-002
EudraCT Number
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

Efficacy of ivabradine in combination with beta-blockers vs up-titration of beta-blockers in daily practice

Servier Protocol Code
Control-2
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4

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