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A Phase 1a/1b, Open-label, Multicenter Trial Investigating the Safety, Tolerability, and Preliminary Anti-neoplastic Activity of S095029 (Anti-NKG2A) as Monotherapy and in Combination With Sym021 (Anti-PD-1) in Patients With Advanced Solid Tumor Malignancies Followed by an Expansion Part With Triplet Combinations of S095029 and Sym021 and an Anti-HER2 mAb or Anti-EGFR mAbs (Futuximab/Modotuximab) in Patients With Metastatic Gastric or Colorectal Cancers

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Study Phase

Phase 1

Therapeutic Area


IndicationMetastatic Colorectal Cancers, Metastatic Gastric Cancers, Solid tumors
SponsorInstitut de Recherches Internationales Servier
Active substance/
Medical device


Active Substance CodeS095029
Protocol CodeCL1-95029-001
NCT CodeNCT05162755

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