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Efficacy and safety of 3 doses of S 47445 versus placebo in patients with Alzheimer’s disease at mild to moderate stages with depressive symptoms. A 24-week international, multi-centre, randomized, double-blind, placebo-controlled phase II study in monotherapy followed by an optional 28-week extension period in co-administration with donepezil.

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Study Phase

Phase 2

Therapeutic Area

Neuropsychiatric Diseases

IndicationAlzheimer's disease
SponsorInstitut de Recherches Internationales Servier (I.R.I.S)
Active substance/
Medical device


Active Substance CodeS047445
Protocol CodeCL2-47445-011
EudraCT Code2014-001519-38
NCT CodeNCT02626572

Documents and links

Results summary READ MORE

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