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An Open-Label, Dose-escalation, Phase I/IIa Study to Determine the Maximum Tolerated Dose, Recommended Dose, Efficacy, Pharmacokinetics and Pharmacodynamics of the dual VEGFR-FGFR Tyrosine Kinase Inhibitor, E-3810, Given Orally as Single Agent to Patients With Advanced Solid Tumours.

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Study Phase

Phase 1-2

Therapeutic Area


IndicationSolid tumors
SponsorInstitut de Recherches Internationales Servier (I.R.I.S)
Active substance/
Medical device


Active Substance CodeS080881
Protocol CodeCL1-80881-007
EudraCT Code2010-019121-37
NCT CodeNCT01283945

Documents and links

Results summary READ MORE
Scientific publication READ MORE

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